{"id":97268,"title":"Rhizome AI - Know what the FDA thinks","tagline":"Instantly answer regulatory questions with up to 1,000 documents from public health authority databases without hallucinations","body":"Hi all - I’m [Chetan](http://linkedin.com/in/chemishra), the founder of [Rhizome AI](https://rhizomeai.com/).\n\n# _Tl;dr_\n\n_What has the FDA’s feedback been on real world evidence in review comments?_ \n\nWe help life science companies know what the FDA thinks.\n\nRegulatory affairs teams ask a question and get an answer backed by terabytes of regulatory \u0026 clinical databases from the US, EU, etc.\n\nUnlike ChatGPT, Rhizome reads up to 1,000 documents per question, accompanies each statement with a citation, and doesn’t hallucinate.\n\n**_Ask_**: If you know any biotech or medtech leaders (esp if they’re regulatory affairs or R\u0026D), I’d appreciate [an intro](https://calendly.com/mishrachetan/launch-yc)!\n\nUltimately we want all reg affairs teams to be as informed as [the most regulatory man in the world](https://youtube.com/shorts/whOX6BuvgMI). \n\n### 😖 The problem: Knowing what the FDA thinks\n\nThe FDA is the customer of every function in life sciences. It doesn’t matter whether you are regulatory affairs, R\u0026D, quality, manufacturing, commercial, etc.\n\nAt the same time, it’s difficult to understand their thinking. Guidance documents are high level and vague. The only alternative is doing (or paying a consultant to do) manual, painful research on past decisions they’ve made and understand _why_. Other regulators around the globe are no easier.\n\nChatGPT / Claude / etc. have only made it worse\n\n* They trust their knowledge and only look up what they feel the need to. This means low-latency, but high-hallucination research\n* Even when they retrieve sources, at most, it’s a few dozen. It’s also liable to include lots of internet junk mixed in with the authoritative government databases the industry trusts\n* They don’t make it easy to check citations. They cite a 1200 page PDF and you don’t really know where to dig inside it.\n\n### ✨ The Solution: Hallucination-free, deep research for life sciences\n\nRhizome Ask solves this problem by providing hallucination-free and thorough deep research for the life sciences. There’s a few key things our customers like:\n\n* We didn’t have a single hallucination reported in 2025. \n* Every statement comes with a citation\n* We read up to 1,000 documents per question in a few minutes before writing an answer. We’re continuously extending this limit.\n\n \n\nHere’s a quick peek at the product:\n\n![uploaded image](/media/?type=post\u0026id=97268\u0026key=user_uploads/668813/dbc9e5d3-d827-4dfe-8b2d-52dfab9bb2b1)\n\nOur customers love it. A few testimonials:\n\n* “_Last time we did this research, we spent weeks. Rhizome found the answer immediately_.” - a VP of reg affairs at a clinical-stage biotech\n* _“Chetan idk what kind of magic you all did here, it’s so good” -_ a VP of reg affairs at a biotech with multiple products on the market\n* _“I would cry if I lost access to Rhizome” -_ an RA manager at a drug delivery device company\n* “_10 minutes of work can accomplish what would have taken weeks._” a device engineer at a pharma company\n\n### 🤝 Who am I\n\n![uploaded image](/media/?type=post\u0026id=97268\u0026key=user_uploads/668813/85808e43-72d1-4d28-b536-7fd8d4af6c5c)\n\nA bit about my background. \n\nI joined EvolutionaryScale as their first product engineer, launching an AI inference platform to help scientists design proteins. I joined Instabase as #16 helping banks with document \u0026 imaging processing, closing $7m as the technical lead. \n\nWhen looking to start my own company, I realized we saw many AI startups focused on drug discovery, but a _lot_ less attention bringing those products to market. \n\n# 🙏 My ask: Connections with regulatory affairs, quality, or R\u0026D leaders in life sciences\n\nDo you know any regulatory affairs, quality, or R\u0026D leaders in life sciences? It would be awesome to chat with them!\n\nOther ways you can help:\n\n* Follow us on [Linkedin](https://www.linkedin.com/company/rhizomeai/)\n* Share this post with your friends / family in life sciences!\n* Learn more about us at [rhizomeai.com](http://rhizomeai.com)","slug":"PIq-rhizome-ai-know-what-the-fda-thinks","created_at":"2026-01-29T17:20:48.065Z","updated_at":"2026-06-20T17:01:24.083Z","total_vote_count":13,"url":"https://www.ycombinator.com/launches/PIq-rhizome-ai-know-what-the-fda-thinks","share_image_url":"https://www.ycombinator.com/media/?type=post\u0026id=97268\u0026key=user_uploads/668813/85808e43-72d1-4d28-b536-7fd8d4af6c5c","company":{"id":31176,"name":"Rhizome AI","slug":"rhizome-ai","url":"https://rhizomeai.com/","logo":"https://bookface-images.s3.amazonaws.com/small_logos/3bcee7f777db1539a455395ef7d0f4174a507995.png","batch":"Winter 2026","industry":"B2B","tags":[],"search_path":"https://bookface.ycombinator.com/company/31176"}}