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SiPhox Health

Wearable and At-Home health monitoring with silicon photonic chips

We are developing a new paradigm for consumer health tech wearables by replacing a 100lb optical instrument with an area of silicon smaller than a postage stamp.
Active Founders
Michael Dubrovsky
Michael Dubrovsky
Co-Founder
I'm a serial entrepreneur interested in challenging myself and changing the world with nanotechnology.
Diedrik Vermeulen
Diedrik Vermeulen
Founder
Diedrik is one of the founders of SiPhox and serves as its Chief Executive Officer. Diedrik brings to SiPhox extensive expertise and experience in the development of optical systems on a chip. Prior to joining SiPhox, Diedrik was the director of engineering at Analog Photonics and a research scientist at the Massachusetts Institute of Technology. Diedrik has 28 patents and 108 publications and is recognized as the world expert in optical fiber, free-space and chip-to-chip coupling.
Company Launches
πŸ’‰ 🩸SiPhox Health GLP Monitoring
See original launch post

TL;DR: We've launched the SiPhox Health GLP Monitoring Panel: at-home blood testing and body composition tracking built specifically for people on GLP-based therapy (Ozempic, Zepbound, Retatrutide, etc.).

βœ… 40+ lab markers covering metabolism, lipids, liver, kidney, thyroid, hormones, and nutrition

βœ… Painless upper arm patch at-home collection β€” no lab visits, no appointments, no finger pricks

βœ… In-app body-composition scanner to track fat loss vs. muscle preservation

βœ… GLP Tolerance Score β€” built from your labs, body comp, and symptom check-ins

βœ… Symptom check-ins for fatigue, brain fog, hair shedding, GI issues, and muscle loss

βœ… Wearable integration β€” Apple Health, Oura, Whoop, Dexcom, Libre, etc.

βœ… Upload third-party labs (Quest, Labcorp, etc.) for a complete picture in one dashboard

βœ… $199 β€” HSA/FSA eligible

πŸ”— Start monitoring: http://siphoxhealth.com/glp-monitoring

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πŸ”¨ Why We Built This

We're Getting Into the GLP Game β€” But Not With a Me-Too Product

30 million Americans are currently on GLP drugs. That number is going up. Access is getting easier, prices are falling, and the longevity research on low-dose GLP therapy is compelling enough that it's not hard to imagine most adults cycling on and off these medications eventually, not just for weight loss, but for metabolic health and lifespan.

There are plenty of places to buy Ozempic, but the monitoring and optimization infrastructure is not there yet. The biology of GLP therapy is more complicated than the weight loss headline suggests:

🚫 Muscle loss is hidden by the scale. Fast weight loss often means lean mass loss, not just fat. Standard weight tracking can't tell the difference.

🚫 Side effects are downstream signals. Fatigue, brain fog, hair shedding, and constipation aren't random β€” they're often markers of caloric under-fueling, nutrient depletion, or dehydration pressure that bloodwork would catch early.

🚫 Prescribers don't monitor the full picture. Most GLP patients get minimal follow-up labs, if any. HbA1c, ApoB, ferritin, B12, testosterone, thyroid β€” none of these are standard-of-care during treatment.

🚫 Weight alone is a bad success metric. Losing 24 lbs while losing 6 lbs of muscle and depleting your ferritin is not the same as losing 24 lbs of fat.

The Solution: A Monitoring Loop Built for GLP Therapy

We've served 50,000+ users with at-home blood testing. GLP users are a distinct population with distinct needs, so we built a product specifically for them. The SiPhox GLP Monitoring Panel connects labs, body composition, and symptom tracking into one continuous loop so you can see what the drug is actually doing to your biology and course-correct before small problems become bigger ones.


πŸ’‘ What You Get

βœ… 40+ Lab Markers β€” GLP-Specific Panel

Not a generic wellness panel. Built around the markers that matter when appetite, weight, hydration, and body composition are actively changing:

  • Metabolism: HbA1c, eAG, C-Peptide
  • Lipids & heart: ApoB, LDL, HDL, Triglycerides, hsCRP
  • Liver: ALT, AST, ALP, bilirubin, albumin
  • Kidney & hydration: BUN, creatinine, eGFR, BUN:Cr ratio
  • Thyroid: TSH, Free T4
  • Hormones: Testosterone (total + free + %), SHBG, cortisol
  • Nutrition: Vitamin D, B12, folate, ferritin, iron studies (Iron, UIBC, TIBC, Iron Saturation), total protein

βœ… Painless At-Home Collection

Collected via our Easydraw arm patch, no venous draw, no finger prick, no lab visit. Mail it back, and the results appear in your dashboard.

βœ… Body-Composition Scanning

In-app scanner tracks fat loss vs. lean mass preservation between tests.

βœ… GLP Tolerance Score

A composite score built from labs, body comp, and symptom check-ins. Tracks how well your body is handling therapy at each stage: baseline β†’ titration β†’ maintenance.

βœ… Symptom & Side-Effect Tracking

Track fatigue, brain fog, hair shedding, GI issues, and muscle soreness between tests. Connects subjective experience to objective lab data.

βœ… Detailed Analysis & Personalized Insights

Interpret what's moving in the right direction, what deserves a conversation with your prescriber, and what to adjust in diet, training, or supplementation built around your specific results.

πŸ”— Start monitoring: http://siphoxhealth.com/glp-monitoring



πŸ“ˆ Why Now?

GLP drugs are the fastest-growing drug class in history. Next-gen peptides like retatrutide, orforglipron, cagrilintide are coming. The longevity use case is expanding the addressable population well beyond obesity treatment. And monitoring has not kept pace with any of it.

Most patients are flying blind. Prescribers don't have the bandwidth for individualized follow-up. Labs are ordered inconsistently, if at all. No one is connecting weight, body composition, symptoms, and biomarkers in a single continuous view.

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🏒 For Businesses: White-Label the GLP Monitoring

Running a GLP prescribing platform, a metabolic health clinic, a wellness app, or a supplement brand with a GLP-adjacent audience? You can white-label or co-brand the entire monitoring program.

What the partner program gives you:

βœ… White-label or co-branded kit and dashboard under your brand

βœ… Full panel access + API integration for embedding results in your own product

βœ… Partner dashboard to track your clients' health journeys and customize next steps with real biomarker data

βœ… Pre/post protocol testing to prove efficacy and reduce churn

βœ… CLIA/CAP-accredited lab processing β€” same quality as traditional venous draws

βœ… Account management, biomarker interpretation training, and marketing support

Patients are 3x more likely to stay engaged with a health program backed by real biomarker data.

πŸ”— Partner inquiry: siphoxhealth.com/partner

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🀝 For Health Coaches: Refer and Earn

If you work with people on GLP therapy as a health coach, personal trainer, or content creator, our affiliate program is built for you.

No cost to join. No hidden fees. Your referrals get a better monitoring product and better outcomes; you get a meaningful revenue stream.

πŸ”— Join the affiliate program: siphoxhealth.com/affiliate-program


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About SiPhox Health

SiPhox Health, backed by Khosla Ventures, Intel Capital, and Y Combinator, is a full-stack home blood testing company founded at MIT. We've tested 1M+ biomarkers across 50,000+ users. Our long-term mission is SiPhox Home β€” a silicon photonic chip that delivers instant blood test results from home. The GLP Monitoring Panel runs on our existing CLIA/CAP-accredited lab infrastructure and Easydraw arm collection patch.

Previous Launches
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Your free lab test and health optimization copilot
Upload your recent blood test results for free and receive aΒ clear, easy-to-understand analysis of your health data.
At-home health testing is too expensive and slow. We’re fixing that.
Jobs at SiPhox Health
Burlington, MA, US
$130K - $230K
3+ years
Boston, MA, US
$100K - $150K
1+ years
Boston, MA, US / Burlington, MA, US
$150K - $200K
6+ years
SiPhox Health
Founded:2020
Batch:Summer 2020
Team Size:63
Status:
Active
Location:Boston
Primary Partner:Jared Friedman